Percutaneous CT-Guided Radiofrequency Ablation of Solitary Small Renal Masses: A Single Center Experience.
Rofo
; 187(7): 577-83, 2015 Jul.
Article
em En
| MEDLINE
| ID: mdl-25962750
ABSTRACT
PURPOSE:
To analyze the outcome of patients undergoing percutaneous CT-guided radiofrequency ablation (RFA) of small renal masses (SRM) at a single center during a ten-year time period. MATERIALS ANDMETHODS:
Patient records of renal RFAs (07/2003â-â11/2013) were reviewed. Indications were SRM suspicious of malignancy on imaging and one of the following severe comorbidity; old age; solitary kidney; impaired renal function; patient wish. Biopsy was performed at the time of RFA. Patients were excluded if no follow-up was available. Patient and procedural characteristics were recorded. Survival rates were calculated using the Kaplan-Meier's method and compared with log-rank or cox tests.RESULTS:
38 patients (16 females, mean age 70.0 years [range 52â-â87]) presenting with a solitary SRM were included in the study. Biopsy showed malignancy in 29 patients; 9 had benign tumors. 26 patients suffered from cardiovascular, respiratory or hepatic comorbidities. Technical success (complete ablation on first follow-up) was achieved in 95â% of cases. Two major complications (bowel perforation; hematothorax) occurred. The 3- and 7-year overall survival (OS) [any cause] rates were 73.4â±â0.8â% and 50.3â±â1.0â%, respectively (mean follow-up 54.6 months, range 1â-â127). 4 recurrences and 2 metastases were observed. The presence of comorbidities was the only independent predictor of OS.âThere was no difference in survival between patients with benign and malignant tumors.CONCLUSION:
RFA of SRM is successful in a large percentage of cases with a low complication rate and durable local control. As RFA is typically performed in multimorbid patients, overall survival seems to depend primarily on comorbidities rather than cancer progression. Key Points â¢âRFA of SRM is technically successful in the majority of cases. â¢âRFA leads to a high degree of local tumor control. â¢âPost-RFA most patients ultimately die of comorbidities. â¢âOverall survival post-RFA does not significantly differ between benign and malignant tumors in multimorbid patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma de Células Renais
/
Ablação por Cateter
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Neoplasias Renais
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
Limite:
Aged
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Aged80
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Rofo
Ano de publicação:
2015
Tipo de documento:
Article