The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes.

Wilkinson, B; Grepo, N; Thompson, B L; Kim, J; Wang, K; Evgrafov, O V; Lu, W; Knowles, J A; Campbell, D B

Wilkinson, B; Grepo, N; Thompson, B L; Kim, J; Wang, K; Evgrafov, O V; Lu, W; Knowles, J A; Campbell, D B.

Afiliação

Wilkinson B; Development, Stem Cells, and Regeneration Ph.D. Program, University of Southern California, Los Angeles, CA, USA.
Grepo N; Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Thompson BL; Division of Occupational Science and Occupational Therapy, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA.
Kim J; 1] Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA [2] Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Wang K; 1] Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA [2] Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Evgrafov OV; 1] Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA [2] Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Lu W; 1] Broad Center for Regenerative Medicine and Stem Cell Research, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA [2] Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Knowles JA; 1] Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA [2] Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Campbell DB; 1] Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA [2] Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Transl Psychiatry ; 5: e568, 2015 May 19.

Article em En | MEDLINE | ID: mdl-25989142

Assuntos

Transtorno Autístico/genética; Proteínas de Ligação a DNA/genética; Células-Tronco Neurais/metabolismo; RNA Mensageiro/genética; RNA não Traduzido/genética; Fatores de Transcrição/genética; Transtorno do Espectro Autista/genética; Células Cultivadas; Regulação da Expressão Gênica no Desenvolvimento; Técnicas de Silenciamento de Genes; Humanos; RNA Interferente Pequeno

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Fatores de Transcrição / RNA Mensageiro / RNA não Traduzido / Proteínas de Ligação a DNA / Células-Tronco Neurais Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Transl Psychiatry Ano de publicação: 2015 Tipo de documento: Article

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