Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity.

Vaisar, Tomás; Tang, Chongren; Babenko, Ilona; Hutchins, Patrick; Wimberger, Jake; Suffredini, Anthony F; Heinecke, Jay W

Vaisar, Tomás; Tang, Chongren; Babenko, Ilona; Hutchins, Patrick; Wimberger, Jake; Suffredini, Anthony F; Heinecke, Jay W.

Afiliação

Vaisar T; Department of Medicine, University of Washington, Seattle, WA 98105.
Tang C; Department of Medicine, University of Washington, Seattle, WA 98105.
Babenko I; Department of Medicine, University of Washington, Seattle, WA 98105.
Hutchins P; Department of Medicine, University of Washington, Seattle, WA 98105.
Wimberger J; Department of Medicine, University of Washington, Seattle, WA 98105.
Suffredini AF; Critical Care Medicine Department, National Institutes of Health, Bethesda, MD 20892.
Heinecke JW; Department of Medicine, University of Washington, Seattle, WA 98105.

J Lipid Res ; 56(8): 1519-30, 2015 Aug.

Article em En | MEDLINE | ID: mdl-25995210

Assuntos

HDL-Colesterol/metabolismo; Proteoma/metabolismo; Adulto; Animais; HDL-Colesterol/sangue; HDL-Colesterol/química; Citoproteção; Endotoxinas/toxicidade; Humanos; Inflamação/sangue; Inflamação/metabolismo; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Masculino; Camundongos; Miocárdio/citologia; Miocárdio/metabolismo; Proteína Amiloide A Sérica/deficiência; Proteína Amiloide A Sérica/metabolismo

Palavras-chave

apolipoproteins; atherosclerosis; high density lipoprotein; inflammation; mass spectrometry; proteomics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteoma / HDL-Colesterol Tipo de estudo: Risk_factors_studies Limite: Adult / Animals / Humans / Male Idioma: En Revista: J Lipid Res Ano de publicação: 2015 Tipo de documento: Article

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