Cyclic phosphatidic acid inhibits the secretion of vascular endothelial growth factor from diabetic human coronary artery endothelial cells through peroxisome proliferator-activated receptor gamma.

Tsukahara, Tamotsu; Tsukahara, Ryoko; Haniu, Hisao; Matsuda, Yoshikazu; Murakami-Murofushi, Kimiko

Tsukahara, Tamotsu; Tsukahara, Ryoko; Haniu, Hisao; Matsuda, Yoshikazu; Murakami-Murofushi, Kimiko.

Afiliação

Tsukahara T; Department of Molecular Pharmacology and Neuroscience, Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan. Electronic address: ttamotsu@nagasaki-u.ac.jp.
Tsukahara R; Endowed Research Division of Human Welfare Sciences, Ochanomizu University, 2-1-1, Ohtsuka, Bunkyo-ku, Tokyo 112-8610, Japan; Science and Education Center, Ochanomizu University, 2-1-1 Ohtsuka, Bunkyo-ku, Tokyo 112-861, Japan.
Haniu H; Institue for Biomedical Sciences, Shinshu University Interdisciplinary Cluster for Cutting Edge Research 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.
Matsuda Y; Clinical Pharmacology Educational Center, Nihon Pharmaceutical University, Ina-machi, Saitama 362-0806, Japan.
Murakami-Murofushi K; Science and Education Center, Ochanomizu University, 2-1-1 Ohtsuka, Bunkyo-ku, Tokyo 112-861, Japan.

Mol Cell Endocrinol ; 412: 320-9, 2015 Sep 05.

Article em En | MEDLINE | ID: mdl-26007326

Assuntos

Vasos Coronários/patologia; Células Endoteliais/metabolismo; PPAR gama/fisiologia; Ácidos Fosfatídicos/farmacologia; Fator A de Crescimento do Endotélio Vascular/metabolismo; Aterosclerose/metabolismo; Aterosclerose/patologia; Movimento Celular; Proliferação de Células; Células Cultivadas; Diabetes Mellitus Tipo 2/metabolismo; Diabetes Mellitus Tipo 2/patologia; Células Endoteliais/efeitos dos fármacos; Compostos Heterocíclicos com 1 Anel/farmacologia; Humanos

Palavras-chave

Cyclic phosphatidic acid; Diabetic human coronary artery endothelial cells; Peroxisome proliferator-activated receptor gamma; VEGF

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Fosfatídicos / Vasos Coronários / Células Endoteliais / Fator A de Crescimento do Endotélio Vascular / PPAR gama Limite: Humans Idioma: En Revista: Mol Cell Endocrinol Ano de publicação: 2015 Tipo de documento: Article

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