Molecular Interactions of ß-(1â3)-Glucans with Their Receptors.
Molecules
; 20(6): 9745-66, 2015 May 27.
Article
em En
| MEDLINE
| ID: mdl-26023937
ABSTRACT
ß-(1â3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi. Research has now established that ß-(1â3)-glucans can trigger different immune responses and act as efficient immunostimulating agents. They constitute prevalent sources of carbons for microorganisms after subsequent recognition by digesting enzymes. Nevertheless, mechanisms associated with both roles are not yet clearly understood. This review focuses on the variety of elucidated molecular interactions that involve these natural or synthetic polysaccharides and their receptors, i.e., Dectin-1, CR3, glycolipids, langerin and carbohydrate-binding modules.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adjuvantes Imunológicos
/
Antígeno de Macrófago 1
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Lectinas Tipo C
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Glucana 1,3-beta-Glucosidase
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Beta-Glucanas
Limite:
Humans
Idioma:
En
Revista:
Molecules
Ano de publicação:
2015
Tipo de documento:
Article