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The TMPRSS2-ERG Gene Fusion Blocks XRCC4-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP Inhibition.
Chatterjee, Payel; Choudhary, Gaurav S; Alswillah, Turkeyah; Xiong, Xiahui; Heston, Warren D; Magi-Galluzzi, Cristina; Zhang, Junran; Klein, Eric A; Almasan, Alexandru.
Afiliação
  • Chatterjee P; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio. School of Biomedical Sciences, Kent State University, Kent, Ohio.
  • Choudhary GS; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio. Department of Pathology, Case Western Reserve University School of Medicine, Ohio.
  • Alswillah T; Department of Chemistry, Cleveland State University, Cleveland, Ohio.
  • Xiong X; Department of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
  • Heston WD; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
  • Magi-Galluzzi C; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio. Robert J. Tomisch Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio.
  • Zhang J; Department of Radiation Oncology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
  • Klein EA; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.
  • Almasan A; Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio. Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio. almasaa@ccf.org.
Mol Cancer Ther ; 14(8): 1896-906, 2015 Aug.
Article em En | MEDLINE | ID: mdl-26026052

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Tolerância a Radiação / Proteínas de Fusão Oncogênica / Proteínas de Ligação a DNA / Reparo do DNA por Junção de Extremidades / Inibidores de Poli(ADP-Ribose) Polimerases Limite: Humans / Male Idioma: En Revista: Mol Cancer Ther Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Tolerância a Radiação / Proteínas de Fusão Oncogênica / Proteínas de Ligação a DNA / Reparo do DNA por Junção de Extremidades / Inibidores de Poli(ADP-Ribose) Polimerases Limite: Humans / Male Idioma: En Revista: Mol Cancer Ther Ano de publicação: 2015 Tipo de documento: Article