Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis.
Autophagy
; 11(7): 1130-45, 2015.
Article
em En
| MEDLINE
| ID: mdl-26039325
Palavras-chave
BUN, blood urea nitrogen; CASP3, caspase 3, apoptosis-related cysteine peptidase; Cdh5, cadherin 5; DM, diabetes mellitus; DN, diabetic nephropathy; ESRD, end-stage renal disease; GBM, glomerular basement membrane; GEC, glomerular endothelial cells; GFB, glomerular filtration barrier; MAP1LC3A/B/LC3A/B), microtubule-associated protein 1 light chain 3 α/ß; MTOR, mechanistic target of rapamycin; Nphs2, nephrosis 2, podocin; SQSTM1, sequestosome 1; STZ, streptozotocin; TEM, transmission electron microscopy; TUBA, tubulin; autophagy; diabetic nephropathy; endothelial cells; podocytes; proteinuria; sclerosis; α, WT1, Wilms tumor 1
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
6_ODS3_enfermedades_notrasmisibles
Base de dados:
MEDLINE
Assunto principal:
Autofagia
/
Células Endoteliais
/
Nefropatias Diabéticas
/
Podócitos
Limite:
Animals
Idioma:
En
Revista:
Autophagy
Ano de publicação:
2015
Tipo de documento:
Article