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[Gallopamil and chlorthalidone versus atenolol and chlorthalidone in the treatment of obstructive hypertrophic cardiomyopathy in patients with arterial hypertension: polycardiographic evaluation of the systolic and diastolic function of the left ventricle]. / Gallopamil e clortalidone versus atenololo e clortalidone nella terapia della cardiomiopatia ipertrofica ostruttiva di pazienti con ipertensione arteriosa: valutazione policardiografica della funzione sistolica e diastolica ventricolare sinistra.
Cardiologia ; 34(8): 695-9, 1989 Aug.
Article em It | MEDLINE | ID: mdl-2605580
In 13 patients, affected by hypertrophic obstructive cardiomyopathy (HOCM) and essential hypertension, antihypertensive-efficacy and effects of a new calcium-channel blocker (gallopamil) associated with a diuretic agent (chlorthalidone) on left ventricular systolic and diastolic performance assessed by phonocardiographic methods. The results were compared to those obtained, in the same group of patients, with a selective beta-blocker (atenolol) associated with the same diuretic agent (chlorthalidone). With both therapeutic regimens a statistically significant reduction of systolic and diastolic arterial pressure was observed; both agents were able to reduce hemodynamic gradient in systole which characterize HOCM; however, the treatment with gallopamil plus chlorthalidone determined greater effects on left ventricular diastolic function as compared to the treatment with atenolol plus chlorthalidone; both treatments determined bradycardia.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atenolol / Cardiomiopatia Hipertrófica / Galopamil / Clortalidona Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: It Revista: Cardiologia Ano de publicação: 1989 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atenolol / Cardiomiopatia Hipertrófica / Galopamil / Clortalidona Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: It Revista: Cardiologia Ano de publicação: 1989 Tipo de documento: Article