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A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells.
Mailloux, Ryan; Fu, Accalia; Florian, Maria; Petrov, Ivan; Chen, Qixuan; Coughlan, Melanie C; Laziyan, Mahemuti; Yan, Jin; Caldwell, Don; Patry, Dominique; Lalande, Michelle; Wang, Gen-Sheng; Willmore, William; Jin, Xiaolei.
Afiliação
  • Mailloux R; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada; Institute of Biochemistry, Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada.
  • Fu A; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada; Institute of Biochemistry, Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada.
  • Florian M; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada; Institute of Biochemistry, Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada.
  • Petrov I; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada.
  • Chen Q; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada.
  • Coughlan MC; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada.
  • Laziyan M; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada; Institute of Biochemistry, Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada.
  • Yan J; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada.
  • Caldwell D; Scientific Services Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, K1A 0K9 Ontario, Canada.
  • Patry D; Scientific Services Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, K1A 0K9 Ontario, Canada.
  • Lalande M; Scientific Services Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, K1A 0K9 Ontario, Canada.
  • Wang GS; Scientific Services Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, K1A 0K9 Ontario, Canada.
  • Willmore W; Institute of Biochemistry, Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario K1S 5B6, Canada.
  • Jin X; Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario K1A 0K9, Canada. Electronic address: dawn.jin@hc-sc.gc.ca.
Toxicology ; 334: 81-93, 2015 Aug 06.
Article em En | MEDLINE | ID: mdl-26066519
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Magreza / Ilhotas Pancreáticas / Misturas Complexas / Diabetes Mellitus / Poluentes Ambientais / Insulina / Insulinoma / Obesidade Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Toxicology Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Magreza / Ilhotas Pancreáticas / Misturas Complexas / Diabetes Mellitus / Poluentes Ambientais / Insulina / Insulinoma / Obesidade Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Toxicology Ano de publicação: 2015 Tipo de documento: Article