Host Range Restriction of Epstein-Barr Virus and Related Lymphocryptoviruses.
J Virol
; 89(17): 9133-6, 2015 Sep.
Article
em En
| MEDLINE
| ID: mdl-26085168
ABSTRACT
Epstein-Barr-related herpesviruses, or lymphocryptoviruses (LCV), naturally infect humans and nonhuman primates (NHP), but their host range is not well characterized. Using LCV and B cells from multiple species of Hominidae and Cercopithecidae, we show that LCV can immortalize B cells from some nonnative species but that growth transformation is restricted to B cells from their own family of hominoids or Old World NHP, suggesting a high degree of LCV adaptation to their natural primate host.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cercopithecidae
/
Lymphocryptovirus
/
Herpesvirus Humano 4
/
Especificidade de Hospedeiro
/
Doenças dos Macacos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Virol
Ano de publicação:
2015
Tipo de documento:
Article