Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 &#945;2ß2 Acyl-CoA Dehydrogenase Initiates ß-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.

Yang, Meng; Lu, Rui; Guja, Kip E; Wipperman, Matthew F; St Clair, Johnna R; Bonds, Amber C; Garcia-Diaz, Miguel; Sampson, Nicole S

Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α₂ß₂ Acyl-CoA Dehydrogenase Initiates ß-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.

Yang, Meng; Lu, Rui; Guja, Kip E; Wipperman, Matthew F; St Clair, Johnna R; Bonds, Amber C; Garcia-Diaz, Miguel; Sampson, Nicole S.

Afiliação

Yang M; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Lu R; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Guja KE; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Wipperman MF; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
St Clair JR; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Bonds AC; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Garcia-Diaz M; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.
Sampson NS; Department of Chemistry, Department of Pharmacological Sciences, and Biochemistry and Structural Biology Graduate Program, Stony Brook University , Stony Brook, New York 11794, United States.

ACS Infect Dis ; 1(2): 110-125, 2015 Feb 13.

Article em En | MEDLINE | ID: mdl-26161441

Palavras-chave

17-hydroxy-3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA; 3-oxo-23,24-bisnorchol-4,17-dien-22-oyl-CoA; 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA; cholesterol metabolism; drug target; tuberculosis

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: ACS Infect Dis Ano de publicação: 2015 Tipo de documento: Article

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