Atypical Teratoid Rhabdoid Tumor in a Teenager with Unusual Infiltration Into the Jugular Foramen.
World Neurosurg
; 84(6): 2075.e13-6, 2015 Dec.
Article
em En
| MEDLINE
| ID: mdl-26187115
ABSTRACT
BACKGROUND:
Atypical teratoid rhabdoid tumor is a rare malignant neoplasm that represents 1%-2% of all pediatric central nervous system tumors. Immunohistochemistry plays an important role in establishing the diagnosis with a loss of INI-1 staining in tumor cells. In this case report, we describe a teenager with an unusual presentation and pattern of infiltration of the tumor. CASE DESCRIPTION A 13-year-old boy presented with a history over several months of progressive nausea, weight loss, and hoarseness of voice associated with multiple lower cranial nerve palsies on neurologic examination. Magnetic resonance imaging revealed a large heterogeneously enhancing extra-axial neoplasm with extension and bony expansion of the jugular foramen. After near total resection, neuropathology demonstrated the absence of INI-1 expression consistent with a diagnosis of atypical teratoid rhabdoid tumor.CONCLUSIONS:
This case highlights the diverse clinical presentation and infiltrative potential of atypical teratoid rhabdoid tumors, thus expanding the differential diagnosis of extra-axial tumors invading the jugular foramen.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tumor Rabdoide
/
Neoplasias da Base do Crânio
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Procedimentos Neurocirúrgicos
Tipo de estudo:
Etiology_studies
Limite:
Adolescent
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Humans
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Male
Idioma:
En
Revista:
World Neurosurg
Ano de publicação:
2015
Tipo de documento:
Article