Your browser doesn't support javascript.
loading
Synthesis and Antimicrobial Activities of 3-Methyl-ß-Carboline Derivatives.
Nat Prod Commun ; 10(6): 899-902, 2015 Jun.
Article em En | MEDLINE | ID: mdl-26197512
The ß-carboline alkaloids possess a diverse range of important biochemical effects and pharmacological properties. Sixteen 3-methyl-ß-carboline derivatives were synthesized from indole formaldehyde and nitroethane via the Henry reaction, LAH/THF reduction, the Pictet-Spengler reaction and Pd/C/xylene oxidation, including four 1-substituted and twelve 9-substituted 3-methyl- ß-carboline derivatives. The structures of all the derivatives were confirmed by 1H NMR, 13C NMR and ESI-MS. Most of these 3-methyl-ß-carboline derivatives showed some antibacterial activity.
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carbolinas / Antibacterianos Idioma: En Revista: Nat Prod Commun Ano de publicação: 2015 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carbolinas / Antibacterianos Idioma: En Revista: Nat Prod Commun Ano de publicação: 2015 Tipo de documento: Article