Rh Immunoprophylaxis for Women With a Serologic Weak D Phenotype.
Lab Med
; 46(3): 190-4, 2015.
Article
em En
| MEDLINE
| ID: mdl-26199257
ABSTRACT
It is standard practice for pregnant RhD-negative women who have not already formed anti-D to receive antepartum Rh immunoprophylaxis and, if they deliver an RhD-positive neonate, to receive postpartum Rh immunoprophylaxis. An estimated 0.6% to 1.0% of white women have red blood cells that express a serologic weak D phenotype. Of these women, approximately 80% will have a weak D type 1, 2, or 3 that could be managed safely as RhD-positive. Surveys of laboratory practice reveal a lack of standards for interpreting the RhD type for women with a serologic weak D and for determining their need for Rh immunoprophylaxis. RhD genotyping is recommended to determine the molecular basis of serologic weak D phenotypes in pregnant women as a basis for determining their candidacy for Rh immunoprophylaxis.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sistema do Grupo Sanguíneo Rh-Hr
/
Imunoglobulina rho(D)
Tipo de estudo:
Guideline
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Lab Med
Ano de publicação:
2015
Tipo de documento:
Article