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Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists.
Liu, Bin; Croy, Carrie H; Hitchcock, Stephen A; Allen, Jennifer R; Rao, Zhigang; Evans, David; Bures, Mark G; McKinzie, David L; Watt, Marla Leigh; Stuart Gregory, G; Hansen, Marvin M; Hoogestraat, Paul J; Jamison, James A; Okha-Mokube, Fese M; Stratford, Robert E; Turner, William; Bymaster, Frank; Felder, Christian C.
Afiliação
  • Liu B; Lilly Research Laboratories, Indianapolis, IN 46285, United States. Electronic address: bfliu@lilly.com.
  • Croy CH; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Hitchcock SA; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Allen JR; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Rao Z; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Evans D; Eli Lilly and Company, Windlesham, Surrey, UK.
  • Bures MG; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • McKinzie DL; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Watt ML; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Stuart Gregory G; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Hansen MM; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Hoogestraat PJ; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Jamison JA; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Okha-Mokube FM; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Stratford RE; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Turner W; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Bymaster F; Lilly Research Laboratories, Indianapolis, IN 46285, United States.
  • Felder CC; Lilly Research Laboratories, Indianapolis, IN 46285, United States. Electronic address: felder_christan_c@lilly.com.
Bioorg Med Chem Lett ; 25(19): 4158-63, 2015 Oct 01.
Article em En | MEDLINE | ID: mdl-26299349
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Receptor Muscarínico M1 / Amidas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Receptor Muscarínico M1 / Amidas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2015 Tipo de documento: Article