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Design, synthesis, pharmacological characterization of a fluorescent agonist of the P2Y14 receptor.
Kiselev, Evgeny; Balasubramanian, Ramachandran; Uliassi, Elisa; Brown, Kyle A; Trujillo, Kevin; Katritch, Vsevolod; Hammes, Eva; Stevens, Raymond C; Harden, T Kendall; Jacobson, Kenneth A.
Afiliação
  • Kiselev E; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Balasubramanian R; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Uliassi E; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Brown KA; Department of Pharmacology, University of North Carolina, School of Medicine, Chapel Hill, NC 27599, USA.
  • Trujillo K; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Katritch V; The Bridge Institute, Department of Biological Sciences, Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA 90089, USA.
  • Hammes E; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Stevens RC; The Bridge Institute, Department of Biological Sciences, Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA 90089, USA; The Bridge Institute, Department of Chemistry, Dornsife College of Letters, Arts and Sciences, University of Southern California, Lo
  • Harden TK; Department of Pharmacology, University of North Carolina, School of Medicine, Chapel Hill, NC 27599, USA.
  • Jacobson KA; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: kajacobs@helix.nih.gov.
Bioorg Med Chem Lett ; 25(21): 4733-4739, 2015 Nov 01.
Article em En | MEDLINE | ID: mdl-26303895
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piranos / Desenho de Fármacos / Receptores Purinérgicos P2 / Corantes Fluorescentes / Compostos Heterocíclicos com 3 Anéis Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piranos / Desenho de Fármacos / Receptores Purinérgicos P2 / Corantes Fluorescentes / Compostos Heterocíclicos com 3 Anéis Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2015 Tipo de documento: Article