Rapid screening and identification of compounds with DNA-binding activity from Folium Citri Reticulatae using on-line HPLC-DAD-MS(n) coupled with a post column fluorescence detection system.

Fu, Qingrong; Zhang, Cangman; Lin, Zongtao; Sun, Hongyang; Liang, Yi; Jiang, Haixiu; Song, Zhiling; Wang, Hong; Chen, Shizhong

Fu, Qingrong; Zhang, Cangman; Lin, Zongtao; Sun, Hongyang; Liang, Yi; Jiang, Haixiu; Song, Zhiling; Wang, Hong; Chen, Shizhong.

Afiliação

Fu Q; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address: echo.huisheng@163.com.
Zhang C; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Lin Z; Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN 38163, United States.
Sun H; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Liang Y; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Jiang H; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Song Z; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China.
Wang H; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address: hw9505@bjmu.edu.cn.
Chen S; School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. Electronic address: chenshizhong66@163.com.

Food Chem ; 192: 250-9, 2016 Feb 01.

Article em En | MEDLINE | ID: mdl-26304344

Assuntos

Cromatografia Líquida de Alta Pressão/métodos; Citrus/química; DNA/química; Flavonoides/análise; Fluorescência; Espectrometria de Massas/métodos; Ácidos Carbocíclicos/análise; Ácidos Carbocíclicos/química; Flavonoides/química; Hesperidina/análise; Modelos Lineares; Extratos Vegetais/química; Folhas de Planta/química; Quercetina/análise; Padrões de Referência; Reprodutibilidade dos Testes

Palavras-chave

DNA-binding activity; Feruloylhexaric acids; Flavonoids; Folium Citri Reticulatae; HPLCDADMS(n)EBDNAFLD; p-Coumaroylhexaric acids

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectrometria de Massas / Flavonoides / DNA / Cromatografia Líquida de Alta Pressão / Citrus / Fluorescência Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: En Revista: Food Chem Ano de publicação: 2016 Tipo de documento: Article

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