Total synthesis of avermectin B1a revisited.
J Antibiot (Tokyo)
; 69(1): 31-50, 2016 Jan.
Article
em En
| MEDLINE
| ID: mdl-26350782
ABSTRACT
Avermectins were isolated as compounds possessing anthelmintic activity from the culture broth of Streptomycesavermitilis by Omura and co-workers. Owing to their potent anthelmintic and insecticidal activities, as well as their unique pentacyclic architecture, the avermectin family attracted keen interest from synthetic organic chemists. We have recently completed a more efficient and straightforward total synthesis of avermectin B1a, as compared with previous syntheses.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ivermectina
/
Anti-Helmínticos
Idioma:
En
Revista:
J Antibiot (Tokyo)
Ano de publicação:
2016
Tipo de documento:
Article