Pseudomonas aeruginosa Uses Dihydrolipoamide Dehydrogenase (Lpd) to Bind to the Human Terminal Pathway Regulators Vitronectin and Clusterin to Inhibit Terminal Pathway Complement Attack.

Hallström, Teresia; Uhde, Melanie; Singh, Birendra; Skerka, Christine; Riesbeck, Kristian; Zipfel, Peter F

Hallström, Teresia; Uhde, Melanie; Singh, Birendra; Skerka, Christine; Riesbeck, Kristian; Zipfel, Peter F.

Afiliação

Hallström T; Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany.
Uhde M; Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany.
Singh B; Medical Microbiology, Department of Translational Medicine Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
Skerka C; Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany.
Riesbeck K; Medical Microbiology, Department of Translational Medicine Malmö, Lund University, Skåne University Hospital, Malmö, Sweden.
Zipfel PF; Department of Infection Biology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knoell Institute, Jena, Germany; Faculty of Biology, Friedrich Schiller University, Jena, Germany.

PLoS One ; 10(9): e0137630, 2015.

Article em En | MEDLINE | ID: mdl-26368530

Assuntos

Proteínas de Bactérias/metabolismo; Clusterina/metabolismo; Ativação do Complemento; Complexo de Ataque à Membrana do Sistema Complemento/metabolismo; Di-Hidrolipoamida Desidrogenase/metabolismo; Pseudomonas aeruginosa/enzimologia; Vitronectina/metabolismo; Proteínas de Bactérias/genética; Clusterina/genética; Complexo de Ataque à Membrana do Sistema Complemento/genética; Di-Hidrolipoamida Desidrogenase/genética; Humanos; Viabilidade Microbiana; Ligação Proteica; Estrutura Terciária de Proteína; Pseudomonas aeruginosa/genética; Vitronectina/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Proteínas de Bactérias / Complexo de Ataque à Membrana do Sistema Complemento / Ativação do Complemento / Vitronectina / Clusterina / Di-Hidrolipoamida Desidrogenase Limite: Humans Idioma: En Revista: PLoS One Ano de publicação: 2015 Tipo de documento: Article

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