Your browser doesn't support javascript.
loading
Rotavirus NSP6 localizes to mitochondria via a predicted N-terminal a-helix.
Holloway, Gavan; Johnson, Rebecca I; Kang, Yilin; Dang, Vi T; Stojanovski, Diana; Coulson, Barbara S.
Afiliação
  • Holloway G; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
  • Johnson RI; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
  • Kang Y; Department of Biochemistry and Molecular Biology, The Bio21 Institute, The University of Melbourne, Victoria, Australia.
  • Dang VT; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
  • Stojanovski D; Department of Biochemistry and Molecular Biology, The Bio21 Institute, The University of Melbourne, Victoria, Australia.
  • Coulson BS; Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
J Gen Virol ; 96(12): 3519-3524, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26404393
Specific roles have been ascribed to each of the 12 known rotavirus proteins apart from the non-structural protein 6 (NSP6). However, NSP6 may be present at sites of viral replication within the cytoplasm. Here we report that NSP6 from diverse species of rotavirus A localizes to mitochondria via conserved sequences in a predicted N-terminal a-helix. This suggests that NSP6 may affect mitochondrial functions during rotavirus infection.
Assuntos

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Proteínas não Estruturais Virais / Rotavirus / Mitocôndrias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Gen Virol Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Proteínas não Estruturais Virais / Rotavirus / Mitocôndrias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: J Gen Virol Ano de publicação: 2015 Tipo de documento: Article