Development of dendritic form and function.
Annu Rev Cell Dev Biol
; 31: 741-77, 2015.
Article
em En
| MEDLINE
| ID: mdl-26422333
ABSTRACT
The nervous system is populated by numerous types of neurons, each bearing a dendritic arbor with a characteristic morphology. These type-specific features influence many aspects of a neuron's function, including the number and identity of presynaptic inputs and how inputs are integrated to determine firing properties. Here, we review the mechanisms that regulate the construction of cell type-specific dendrite patterns during development. We focus on four aspects of dendrite patterning that are particularly important in determining the function of the mature neuron (a) dendrite shape, including branching pattern and geometry of the arbor; (b) dendritic arbor size;
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dendritos
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Annu Rev Cell Dev Biol
Ano de publicação:
2015
Tipo de documento:
Article