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A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells.
Castanotto, Daniela; Lin, Min; Kowolik, Claudia; Wang, LiAnn; Ren, Xiao-Qin; Soifer, Harris S; Koch, Troels; Hansen, Bo Rode; Oerum, Henrik; Armstrong, Brian; Wang, Zhigang; Bauer, Paul; Rossi, John; Stein, C A.
Afiliação
  • Castanotto D; Department of Medical Oncology, City of Hope, 1500 East Duarte Road, Duarte CA 91010, USA cstein@coh.org.
  • Lin M; Department of Cancer Immunotherapeutics and Tumor Immunology, City of Hope, 1500 East Duarte Road, Duarte CA 91010, USA.
  • Kowolik C; Department of Molecular Medicine, City of Hope, 1500 East Duarte Road, Duarte CA 91010, USA.
  • Wang L; Pfizer Research Technology Center, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Ren XQ; Pfizer Research Technology Center, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Soifer HS; bioTheranostics, 9640 Towne Center Dr., Suite 100, San Diego, CA 92121, USA.
  • Koch T; Roche, Fremtidsvej 3, Horsholm, DK 2970, Denmark.
  • Hansen BR; Roche, Fremtidsvej 3, Horsholm, DK 2970, Denmark.
  • Oerum H; Roche, Fremtidsvej 3, Horsholm, DK 2970, Denmark.
  • Armstrong B; Department of Neuroscience, City of Hope, 1500 East Duarte Road, Duarte CA 91010, USA.
  • Wang Z; Pfizer Research Technology Center, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Bauer P; Pfizer Research Technology Center, 620 Memorial Drive, Cambridge, MA 02139, USA.
  • Rossi J; Department of Molecular and Cellular Biology, City of Hope, 1500 East Duarte Road, Duarte CA 91010, USA.
  • Stein CA; Department of Medical Oncology, City of Hope, 1500 East Duarte Road, Duarte CA 91010, USA dcastanotto@coh.org.
Nucleic Acids Res ; 43(19): 9350-61, 2015 Oct 30.
Article em En | MEDLINE | ID: mdl-26433227
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos Antissenso / Inativação Gênica / Citoplasma Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligonucleotídeos Antissenso / Inativação Gênica / Citoplasma Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2015 Tipo de documento: Article