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Reduced occurrence of ventilator-associated pneumonia after cardiac surgery using preoperative 0.2% chlorhexidine oral rinse: results from a single-centre single-blinded randomized trial.
Lin, Y J; Xu, L; Huang, X Z; Jiang, F; Li, S L; Lin, F; Ye, Q Y; Chen, M L; Lin, J L.
Afiliação
  • Lin YJ; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China. Electronic address: fjxhlyj@163.com.
  • Xu L; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
  • Huang XZ; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
  • Jiang F; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
  • Li SL; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
  • Lin F; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
  • Ye QY; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
  • Chen ML; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
  • Lin JL; Department of Cardiac Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
J Hosp Infect ; 91(4): 362-6, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26443484
Since mechanical ventilation after cardiac surgery increases the risk of ventilator-associated pneumonia (VAP), we conducted a prospective randomized controlled trial to investigate the effect of preoperative 0.2% chlorhexidine on postoperative VAP. Ninety-four patients scheduled for heart surgery were randomized to a chlorhexidine group (N = 47) or control (saline) group (N = 47). On the day before surgery, patients gargled three times with 0.2% chlorhexidine or saline 30 min after each meal and 5 min after teeth brushing at bedtime. VAP occurred in 8.5% of the chlorhexidine group and in 23.4% of the controls. Preoperative chlorhexidine mouthwash reduced the incidence of postoperative VAP significantly.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD Base de dados: MEDLINE Assunto principal: Cirurgia Torácica / Clorexidina / Desinfetantes / Pneumonia Associada à Ventilação Mecânica / Antissépticos Bucais Tipo de estudo: Clinical_trials / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Hosp Infect Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD Base de dados: MEDLINE Assunto principal: Cirurgia Torácica / Clorexidina / Desinfetantes / Pneumonia Associada à Ventilação Mecânica / Antissépticos Bucais Tipo de estudo: Clinical_trials / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Hosp Infect Ano de publicação: 2015 Tipo de documento: Article