Bufalin Inhibits NCI-H460 Human Lung Cancer Cell Metastasis In Vitro by Inhibiting MAPKs, MMPs, and NF-&#954;B Pathways.

Wu, Shin-Hwar; Hsiao, Yung-Ting; Kuo, Chao-Lin; Yu, Fu-Shun; Hsu, Shu-Chun; Wu, Ping-Ping; Chen, Jaw-Chyun; Hsia, Te-Chun; Liu, Hsin-Chung; Hsu, Wu-Huei; Chung, Jing-Gung

Bufalin Inhibits NCI-H460 Human Lung Cancer Cell Metastasis In Vitro by Inhibiting MAPKs, MMPs, and NF-κB Pathways.

Wu, Shin-Hwar; Hsiao, Yung-Ting; Kuo, Chao-Lin; Yu, Fu-Shun; Hsu, Shu-Chun; Wu, Ping-Ping; Chen, Jaw-Chyun; Hsia, Te-Chun; Liu, Hsin-Chung; Hsu, Wu-Huei; Chung, Jing-Gung.

Afiliação

Wu SH; Institute of Clinical Medical Science, China Medical University, Taichung 404, Taiwan.
Hsiao YT; Division of Critical Care Medicine, Department of Medicine, Changhua Christian Hospital, Changhua 505, Taiwan.
Kuo CL; Department of Biological Science and Technology, China Medical University, Taichung 404, Taiwan.
Yu FS; Department of Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan.
Hsu SC; School of Dentistry, China Medical University, Taichung 404, Taiwan.
Wu PP; Department of Biological Science and Technology, China Medical University, Taichung 404, Taiwan.
Chen JC; School of Pharmacy, China Medical University, Taichung 404, Taiwan.
Hsia TC; Department of Medicinal Botany and Health Applications, Da-Yeh University, Changhua 515, Taiwan.
Liu HC; Department of Internal Medicine, China Medical University Hospital, Taichung 404, Taiwan.
Hsu WH; Department of Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan.
Chung JG; Department of Internal Medicine, China Medical University, Taichung 404, Taiwan.

Am J Chin Med ; 43(6): 1247-64, 2015.

Article em En | MEDLINE | ID: mdl-26446205

Assuntos

Bufanolídeos/farmacologia; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Neoplasias Pulmonares/metabolismo; Metaloproteinase 2 da Matriz/metabolismo; Metaloproteinase 9 da Matriz/metabolismo; NF-kappa B/metabolismo; Linhagem Celular Tumoral; Movimento Celular/efeitos dos fármacos; MAP Quinases Reguladas por Sinal Extracelular/genética; Humanos; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/enzimologia; Neoplasias Pulmonares/genética; Metaloproteinase 2 da Matriz/genética; Metaloproteinase 9 da Matriz/genética; NF-kappa B/genética; Invasividade Neoplásica; Metástase Neoplásica; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

Bufalin; MAPKs; MMPs; NCI-H460 Cells; NF-κB

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bufanolídeos / NF-kappa B / Metaloproteinase 2 da Matriz / Metaloproteinase 9 da Matriz / MAP Quinases Reguladas por Sinal Extracelular / Neoplasias Pulmonares Limite: Humans Idioma: En Revista: Am J Chin Med Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google