Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions.

Kalus, Ina; Rohn, Susanne; Puvirajesinghe, Tania M; Guimond, Scott E; Eyckerman-Kölln, Pieter J; Ten Dam, Gerdy; van Kuppevelt, Toin H; Turnbull, Jeremy E; Dierks, Thomas

Kalus, Ina; Rohn, Susanne; Puvirajesinghe, Tania M; Guimond, Scott E; Eyckerman-Kölln, Pieter J; Ten Dam, Gerdy; van Kuppevelt, Toin H; Turnbull, Jeremy E; Dierks, Thomas.

Afiliação

Kalus I; Fakultät für Chemie, Biochemie I, Universität Bielefeld, Bielefeld, Germany.
Rohn S; Fakultät für Chemie, Biochemie I, Universität Bielefeld, Bielefeld, Germany.
Puvirajesinghe TM; Centre for Glycobiology, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom.
Guimond SE; Centre for Glycobiology, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom.
Eyckerman-Kölln PJ; Fakultät für Chemie, Biochemie I, Universität Bielefeld, Bielefeld, Germany.
Ten Dam G; Department of Biochemistry, University of Nijmegen, Nijmegen, The Netherlands, Center for Molecular Life Sciences, Radboud University Nijmegen Medical Center, Nijmegan, The Netherlands.
van Kuppevelt TH; Department of Biochemistry, University of Nijmegen, Nijmegen, The Netherlands, Center for Molecular Life Sciences, Radboud University Nijmegen Medical Center, Nijmegan, The Netherlands.
Turnbull JE; Centre for Glycobiology, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom.
Dierks T; Fakultät für Chemie, Biochemie I, Universität Bielefeld, Bielefeld, Germany.

PLoS One ; 10(10): e0139853, 2015.

Article em En | MEDLINE | ID: mdl-26448642

Assuntos

Proteoglicanas de Heparan Sulfato/metabolismo; Neuritos/fisiologia; Sulfatases/metabolismo; Sulfotransferases/metabolismo; Animais; Movimento Celular/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Células Cultivadas; Cerebelo/citologia; Cerebelo/metabolismo; Feminino; Fator 2 de Crescimento de Fibroblastos/farmacologia; Fator Neurotrófico Derivado de Linhagem de Célula Glial/farmacologia; Proteínas Hedgehog/farmacologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fator de Crescimento Neural/farmacologia; Neuritos/efeitos dos fármacos; Neurônios/metabolismo; Transdução de Sinais; Sulfatases/deficiência; Sulfatases/genética; Sulfotransferases/deficiência; Sulfotransferases/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfatases / Sulfotransferases / Neuritos / Proteoglicanas de Heparan Sulfato Limite: Animals Idioma: En Revista: PLoS One Ano de publicação: 2015 Tipo de documento: Article

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