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Prodrug AST-003 Improves the Therapeutic Index of the Multi-Targeted Tyrosine Kinase Inhibitor Sunitinib.
Huang, Qiang; Zhou, Changhua; Chen, Xiao; Dong, Bing; Chen, Siqi; Zhang, Ning; Liu, Yawei; Li, Anrong; Yao, Meicun; Miao, Ji; Li, Qing; Wang, Zhong.
Afiliação
  • Huang Q; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China; Centre for Cellular & Structural Biology, Sun Yat-Sen University, Guangzhou, China.
  • Zhou C; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China; Centre for Cellular & Structural Biology, Sun Yat-Sen University, Guangzhou, China.
  • Chen X; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
  • Dong B; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China; Centre for Cellular & Structural Biology, Sun Yat-Sen University, Guangzhou, China.
  • Chen S; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China; Centre for Cellular & Structural Biology, Sun Yat-Sen University, Guangzhou, China.
  • Zhang N; Peking University Cancer Hospital, Beijing Institute for Cancer Research, Beijing, China.
  • Liu Y; Health Division of Guard Bureau, General Staff Department of PLA, Beijing, China.
  • Li A; Ascenta Pharmaceuticals, Guangzhou, Guangdong, P. R. China.
  • Yao M; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
  • Miao J; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
  • Li Q; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China; Centre for Cellular & Structural Biology, Sun Yat-Sen University, Guangzhou, China.
  • Wang Z; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China; Centre for Cellular & Structural Biology, Sun Yat-Sen University, Guangzhou, China.
PLoS One ; 10(10): e0141395, 2015.
Article em En | MEDLINE | ID: mdl-26513662
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Benzoatos / Pró-Fármacos / Inibidores da Angiogênese / Inibidores de Proteínas Quinases / Indóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: PLoS One Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Benzoatos / Pró-Fármacos / Inibidores da Angiogênese / Inibidores de Proteínas Quinases / Indóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: PLoS One Ano de publicação: 2015 Tipo de documento: Article