NAMPT suppresses glucose deprivation-induced oxidative stress by increasing NADPH levels in breast cancer.

Hong, S M; Park, C W; Kim, S W; Nam, Y J; Yu, J H; Shin, J H; Yun, C H; Im, S-H; Kim, K-T; Sung, Y C; Choi, K Y

Hong, S M; Park, C W; Kim, S W; Nam, Y J; Yu, J H; Shin, J H; Yun, C H; Im, S-H; Kim, K-T; Sung, Y C; Choi, K Y.

Afiliação

Hong SM; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Park CW; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Kim SW; Biokogen Inc. POSTECH Biotech Center #226, Pohang, Korea.
Nam YJ; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Yu JH; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Shin JH; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Yun CH; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Im SH; Academy of Immunology and Microbiology (AIM), Institute for Basic Science (IBS), Pohang, Korea.
Kim KT; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.
Sung YC; Academy of Immunology and Microbiology (AIM), Institute for Basic Science (IBS), Pohang, Korea.
Choi KY; Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology (POSTECH), Pohang, Korea.

Oncogene ; 35(27): 3544-54, 2016 07 07.

Article em En | MEDLINE | ID: mdl-26568303

Assuntos

Neoplasias da Mama/metabolismo; Citocinas/metabolismo; Glucose/metabolismo; NADP/metabolismo; Nicotinamida Fosforribosiltransferase/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Acrilamidas/farmacologia; Animais; Western Blotting; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/genética; Hipóxia Celular; Linhagem Celular; Linhagem Celular Tumoral; Citocinas/antagonistas & inibidores; Citocinas/genética; Feminino; Células HCT116; Humanos; Camundongos Endogâmicos BALB C; Camundongos Nus; NAD/metabolismo; Nicotinamida Fosforribosiltransferase/antagonistas & inibidores; Nicotinamida Fosforribosiltransferase/genética; Piperidinas/farmacologia; Interferência de RNA; Espécies Reativas de Oxigênio/metabolismo; Ensaios Antitumorais Modelo de Xenoenxerto/métodos

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Citocinas / Estresse Oxidativo / Nicotinamida Fosforribosiltransferase / Glucose / NADP Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Oncogene Ano de publicação: 2016 Tipo de documento: Article

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