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Determination of unbound fraction of pazopanib in vitro and in cancer patients reveals albumin as the main binding site.
Imbs, Diane-Charlotte; Paludetto, Marie-Noelle; Négrier, Sylvie; Powell, Helen; Lafont, Thierry; White-Koning, Melanie; Chatelut, Etienne; Thomas, Fabienne.
Afiliação
  • Imbs DC; Department of Pharmacology, Institut Claudius-Regaud, IUCT-Oncopole, 1, avenue Irène Joliot-Curie, Toulouse, F-31059, France.
  • Paludetto MN; EA4553 Université Toulouse III Paul-Sabatier, Toulouse, France.
  • Négrier S; Department of Pharmacology, Institut Claudius-Regaud, IUCT-Oncopole, 1, avenue Irène Joliot-Curie, Toulouse, F-31059, France.
  • Powell H; EA4553 Université Toulouse III Paul-Sabatier, Toulouse, France.
  • Lafont T; Centre Léon-Bérard, Lyon, France.
  • White-Koning M; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
  • Chatelut E; Department of Pharmacology, Institut Claudius-Regaud, IUCT-Oncopole, 1, avenue Irène Joliot-Curie, Toulouse, F-31059, France.
  • Thomas F; EA4553 Université Toulouse III Paul-Sabatier, Toulouse, France.
Invest New Drugs ; 34(1): 41-8, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26572909
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Albumina Sérica / Neoplasias / Antineoplásicos Tipo de estudo: Observational_studies Limite: Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Sulfonamidas / Albumina Sérica / Neoplasias / Antineoplásicos Tipo de estudo: Observational_studies Limite: Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2016 Tipo de documento: Article