A review of supportive care and recommended preventive approaches for patients with chronic lymphocytic leukemia.
Expert Rev Hematol
; 9(3): 235-44, 2016 Mar.
Article
em En
| MEDLINE
| ID: mdl-26652692
ABSTRACT
Chronic lymphocytic leukemia (CLL) is the most prevalent type of adult leukemia encountered in the western world. Patients with CLL are typically older, with a median age in the 70s, and are at risk for certain complications due to the disease itself and due to the therapies imparted for this. Patients with CLL are at a higher risk of infections, partly due to disease and partly due to the immune dysfunction induced by treatment, such as purine analogous-based chemoimmunotherapy, which leads to lymphocyte depletion. Infections are a leading cause of complications and death in CLL patients. Also, CLL patients have been shown to have a higher incidence of other malignancies. Despite this knowledge, there are no definite guidelines as to what is the best approach to manage or prevent these associated complications of CLL. In this review, the authors discuss the data available and outline recommendations as to the best way to approach this issue in daily practice.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
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6_ODS3_enfermedades_notrasmisibles
Base de dados:
MEDLINE
Assunto principal:
Infecções Bacterianas
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Viroses
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Leucemia Linfocítica Crônica de Células B
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Anti-Infecciosos
Tipo de estudo:
Etiology_studies
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Guideline
Limite:
Animals
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Humans
Idioma:
En
Revista:
Expert Rev Hematol
Ano de publicação:
2016
Tipo de documento:
Article