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G12V and G12A KRAS mutations are associated with poor outcome in patients with metastatic colorectal cancer treated with bevacizumab.
Fiala, Ondrej; Buchler, Tomas; Mohelnikova-Duchonova, Beatrice; Melichar, Bohuslav; Matejka, Vit Martin; Holubec, Lubos; Kulhankova, Jana; Bortlicek, Zbynek; Bartouskova, Marie; Liska, Vaclav; Topolcan, Ondrej; Sedivcova, Monika; Finek, Jindrich.
Afiliação
  • Fiala O; Department of Oncology and Radiotherapy, Medical School and Teaching Hospital Pilsen, Charles University in Prague, alej Svobody 80, CZ-304 60, Pilsen, Czech Republic. fiala.o@centrum.cz.
  • Buchler T; Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, Plzen, Czech Republic. fiala.o@centrum.cz.
  • Mohelnikova-Duchonova B; Department of Oncology and First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic.
  • Melichar B; Department of Oncology, Palacký University Medical School and Teaching Hospital, Olomouc, Czech Republic.
  • Matejka VM; Department of Oncology, Palacký University Medical School and Teaching Hospital, Olomouc, Czech Republic.
  • Holubec L; Department of Oncology and Radiotherapy, Medical School and Teaching Hospital Pilsen, Charles University in Prague, alej Svobody 80, CZ-304 60, Pilsen, Czech Republic.
  • Kulhankova J; Department of Oncology and Radiotherapy, Medical School and Teaching Hospital Pilsen, Charles University in Prague, alej Svobody 80, CZ-304 60, Pilsen, Czech Republic.
  • Bortlicek Z; Department of Oncology and Radiotherapy, Medical School and Teaching Hospital Pilsen, Charles University in Prague, alej Svobody 80, CZ-304 60, Pilsen, Czech Republic.
  • Bartouskova M; Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
  • Liska V; Department of Oncology, Palacký University Medical School and Teaching Hospital, Olomouc, Czech Republic.
  • Topolcan O; Biomedical Center, Faculty of Medicine in Pilsen, Charles University in Prague, Plzen, Czech Republic.
  • Sedivcova M; Department of Surgery, Medical School and Teaching Hospital Pilsen, Charles University in Prague, Pilsen, Czech Republic.
  • Finek J; Department of Nuclear Medicine, Medical School and Teaching Hospital Pilsen, Charles University in Prague, Pilsen, Czech Republic.
Tumour Biol ; 37(5): 6823-30, 2016 May.
Article em En | MEDLINE | ID: mdl-26662311
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas ras / Alelos / Mutação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Tumour Biol Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas ras / Alelos / Mutação Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Tumour Biol Ano de publicação: 2016 Tipo de documento: Article