[Aberrant expression of long noncoding RNA in prostate cancer].
Zhonghua Nan Ke Xue
; 21(10): 945-8, 2015 Oct.
Article
em Zh
| MEDLINE
| ID: mdl-26665688
ABSTRACT
Prostate cancer (PCa) is one of the most common malignant tumors as well as a frequent cause of cancer-related mortality in men worldwide. The test of serum markers has dramatically improved the early diagnosis of PCa, but its underlying molecular mechanisms are not yet completely identified. Long noncoding RNA (IncRNA) is emerging as a new player in the PCa paradigm demonstrating its potential roles in both oncogenic and tumor suppressive pathways. LncRNA is frequently aberrantly expressed in the majority of PCa cases. This review highlights recent findings of the aberrant expression of lncRNA in PCa and discusses its novel roles in the diagnosis, prediction, prognosis, metastasis, and potential clinical treatment of PCa.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
RNA Longo não Codificante
Tipo de estudo:
Prognostic_studies
/
Screening_studies
Limite:
Humans
/
Male
Idioma:
Zh
Revista:
Zhonghua Nan Ke Xue
Ano de publicação:
2015
Tipo de documento:
Article