Non-viral gene therapy: Gains and challenges of non-invasive administration methods.

Foldvari, Marianna; Chen, Ding Wen; Nafissi, Nafiseh; Calderon, Daniella; Narsineni, Lokesh; Rafiee, Amirreza

Foldvari, Marianna; Chen, Ding Wen; Nafissi, Nafiseh; Calderon, Daniella; Narsineni, Lokesh; Rafiee, Amirreza.

Afiliação

Foldvari M; School of Pharmacy, Waterloo Institute of Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada; Center for Bioengineering and Biotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada. Electronic address: foldvari@uwat
Chen DW; School of Pharmacy, Waterloo Institute of Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada; Center for Bioengineering and Biotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.
Nafissi N; School of Pharmacy, Waterloo Institute of Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada; Center for Bioengineering and Biotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.
Calderon D; School of Pharmacy, Waterloo Institute of Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada; Center for Bioengineering and Biotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.
Narsineni L; School of Pharmacy, Waterloo Institute of Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada; Center for Bioengineering and Biotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.
Rafiee A; School of Pharmacy, Waterloo Institute of Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada; Center for Bioengineering and Biotechnology, University of Waterloo, 200 University Avenue West, Waterloo, ON N2L 3G1, Canada.

J Control Release ; 240: 165-190, 2016 10 28.

Article em En | MEDLINE | ID: mdl-26686079

Assuntos

Biofarmácia/métodos; Técnicas de Transferência de Genes; Terapia Genética/métodos; Animais; Biofarmácia/tendências; Ensaios Clínicos como Assunto/métodos; Técnicas de Transferência de Genes/tendências; Terapia Genética/tendências; Humanos; Neoplasias/genética; Neoplasias/metabolismo; Neoplasias/terapia

Palavras-chave

Biodrugs; Buccal; Cationic lipids; Clinical trials; Cutaneous; Delivery of macromolecules; Gene editing; Gene therapy; Intranasal; Intravaginal; Non-invasive drug delivery; Nucleic acids; Ocular; Otic; Polymers; Protein; Pulmonary; Rectal; Transfection; Vaccines

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biofarmácia / Terapia Genética / Técnicas de Transferência de Genes Limite: Animals / Humans Idioma: En Revista: J Control Release Ano de publicação: 2016 Tipo de documento: Article

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