[Lab-on-a-chip systems in the point-of-care diagnostics]. / Lab-on-a-chip rendszerek a betegágy melletti diagnosztikában.
Orv Hetil
; 156(52): 2096-102, 2015 Dec 27.
Article
em Hu
| MEDLINE
| ID: mdl-26686745
ABSTRACT
The need in modern medicine for near-patient diagnostics being able to accelerate therapeutic decisions and possibly replacing laboratory measurements is significantly growing. Reliable and cost-effective bioanalytical measurement systems are required which - acting as a micro-laboratory - contain integrated biomolecular recognition, sensing, signal processing and complex microfluidic sample preparation modules. These micro- and nanofabricated Lab-on-a-chip systems open new perspectives in the diagnostic supply chain, since they are able even for quantitative, high-precision and immediate analysis of special disease specific molecular markers or their combinations from a single drop of sample. Accordingly, crucial requirements regarding the instruments and the analytical methods are the high selectivity, extremely low detection limit, short response time and integrability into the healthcare information networks. All these features can make the hierarchical examination chain shorten, and revolutionize laboratory diagnostics, evolving a brand new situation in therapeutic intervention.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biomarcadores
/
Sistemas Automatizados de Assistência Junto ao Leito
/
Técnicas de Diagnóstico Molecular
/
Dispositivos Lab-On-A-Chip
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
Hu
Revista:
Orv Hetil
Ano de publicação:
2015
Tipo de documento:
Article