Prehypertension: Defining the Transitional Phenotype.
Curr Hypertens Rep
; 18(1): 2, 2016 Jan.
Article
em En
| MEDLINE
| ID: mdl-26694821
ABSTRACT
More than a simple "transitional stage" defined by covenanted cut points of systolic pressure from 120 to 139 mm of mercury (mm Hg) or a diastolic pressure from 80 to 89 mm Hg, prehypertension should be referred to as a categorical term that defines a specific phenotype in the progression from the "absence of disease" to clinically overt disease. While the currently utilized definition of prehypertension stresses the use of blood pressure cut points to establish the diagnosis, it is of relevance to direct our attention to the structural and functional hemodynamic alterations that occur in response to the two cardinal abnormalities in the development of prehypertension and hypertension autonomic dysfunction and arterial remodeling. Our current review addresses these aspects of the pathophysiology or prehypertension on its progression to hypertension and suggests a new approach to its classification.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pré-Hipertensão
Limite:
Humans
Idioma:
En
Revista:
Curr Hypertens Rep
Ano de publicação:
2016
Tipo de documento:
Article