Pediatric B-Cell Lymphoma With Lymphoblastic Morphology, TdT Expression, MYC Rearrangement, and Features Overlapping With Burkitt Lymphoma.
Pediatr Blood Cancer
; 63(5): 938-40, 2016 May.
Article
em En
| MEDLINE
| ID: mdl-26785246
ABSTRACT
Burkitt lymphoma (BL) and B-lymphoblastic lymphoma are subtypes of pediatric non-Hodgkin lymphoma with different presenting features, treatment, and outcomes. This case report documents a 5-year-old female who presented with B-cell lymphoma with lymphoblastic morphology, terminal deoxynucleotidyl transferase expression, MYC rearrangement, and features overlapping with BL. Genomic microarray analysis identified a gain on the long arm of chromosome 1 without other definitive changes. She was treated according to a BL protocol and remains in remission 16-months after initial diagnosis.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cromossomos Humanos Par 1
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Rearranjo Gênico
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Linfoma de Células B
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Proteínas Proto-Oncogênicas c-myc
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Aberrações Cromossômicas
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Linfoma de Burkitt
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DNA Nucleotidilexotransferase
Tipo de estudo:
Guideline
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Prognostic_studies
Limite:
Child, preschool
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Female
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Humans
Idioma:
En
Revista:
Pediatr Blood Cancer
Ano de publicação:
2016
Tipo de documento:
Article