Dynamics of circulating hypoxia-mediated miRNAs and tumor response in patients with high-grade glioma treated with bevacizumab.

Siegal, Tali; Charbit, Hanna; Paldor, Iddo; Zelikovitch, Bracha; Canello, Tamar; Benis, Arriel; Wong, Michael L; Morokoff, Andrew P; Kaye, Andrew H; Lavon, Iris

Siegal, Tali; Charbit, Hanna; Paldor, Iddo; Zelikovitch, Bracha; Canello, Tamar; Benis, Arriel; Wong, Michael L; Morokoff, Andrew P; Kaye, Andrew H; Lavon, Iris.

Afiliação

Siegal T; Center for Neuro-Oncology, Davidoff Institute of Oncology, Rabin Medical Center, Campus Beilinson, Petach Tikva.
Charbit H; Leslie and Michael Gaffin Center for Neuro-Oncology and Department of Neurology, The Agnes Ginges Center for Human Neurogenetics.
Paldor I; Leslie and Michael Gaffin Center for Neuro-Oncology and Department of Neurology, The Agnes Ginges Center for Human Neurogenetics.
Zelikovitch B; Department of Neurosurgery, Hadassah Hebrew University Medical Center, Jerusalem, Israel; and.
Canello T; Leslie and Michael Gaffin Center for Neuro-Oncology and Department of Neurology, The Agnes Ginges Center for Human Neurogenetics.
Benis A; Leslie and Michael Gaffin Center for Neuro-Oncology and Department of Neurology, The Agnes Ginges Center for Human Neurogenetics.
Wong ML; Leslie and Michael Gaffin Center for Neuro-Oncology and Department of Neurology, The Agnes Ginges Center for Human Neurogenetics.
Morokoff AP; Departments of 4 Neurosurgery and.
Kaye AH; Departments of 4 Neurosurgery and.
Lavon I; Surgery, The Royal Melbourne Hospital and The University of Melbourne, Australia.

J Neurosurg ; 125(4): 1008-1015, 2016 10.

Article em En | MEDLINE | ID: mdl-26799295

Assuntos

Inibidores da Angiogênese/uso terapêutico; Bevacizumab/uso terapêutico; Neoplasias Encefálicas/sangue; Neoplasias Encefálicas/tratamento farmacológico; MicroRNA Circulante/sangue; Glioma/sangue; Glioma/tratamento farmacológico; Adulto; Idoso; Neoplasias Encefálicas/patologia; Feminino; Glioma/patologia; Humanos; Hipóxia; Masculino; Pessoa de Meia-Idade; Gradação de Tumores; Estudos Prospectivos

Palavras-chave

FLAIR = fluid attenuated inversion recovery; GBM = glioblastoma multiforme; HIF-1 = hypoxia-inducible factor-1; PCR = polymerase chain reaction; RANO = Response Assessment in Neuro-Oncology; RQ = relative quantification; TMZ = temozolomide; VEGF = vascular endothelial growth factor; antiangiogenic therapy; bevacizumab; circulating biomarkers; glioblastoma; high-grade glioma; miRNA = microRNA; microRNA; oncology; temozolomide

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Inibidores da Angiogênese / Bevacizumab / MicroRNA Circulante / Glioma Tipo de estudo: Observational_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neurosurg Ano de publicação: 2016 Tipo de documento: Article

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