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Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferase.
Jennings, Benjamin C; Danowitz, Amy M; Wang, Yen-Chih; Gibbs, Richard A; Distefano, Mark D; Fierke, Carol A.
Afiliação
  • Jennings BC; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
  • Danowitz AM; Department of Chemistry and Biochemistry, Mercyhurst University, Erie, PA 16546, USA.
  • Wang YC; Department of Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
  • Gibbs RA; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
  • Distefano MD; Department of Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN 55455, USA.
  • Fierke CA; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: fierke@umich.edu.
Bioorg Med Chem Lett ; 26(4): 1333-6, 2016 Feb 15.
Article em En | MEDLINE | ID: mdl-26803203
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatos de Poli-Isoprenil / Sesquiterpenos / Alquil e Aril Transferases Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatos de Poli-Isoprenil / Sesquiterpenos / Alquil e Aril Transferases Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2016 Tipo de documento: Article