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Joint mouse-human phenome-wide association to test gene function and disease risk.
Wang, Xusheng; Pandey, Ashutosh K; Mulligan, Megan K; Williams, Evan G; Mozhui, Khyobeni; Li, Zhengsheng; Jovaisaite, Virginija; Quarles, L Darryl; Xiao, Zhousheng; Huang, Jinsong; Capra, John A; Chen, Zugen; Taylor, William L; Bastarache, Lisa; Niu, Xinnan; Pollard, Katherine S; Ciobanu, Daniel C; Reznik, Alexander O; Tishkov, Artem V; Zhulin, Igor B; Peng, Junmin; Nelson, Stanley F; Denny, Joshua C; Auwerx, Johan; Lu, Lu; Williams, Robert W.
Afiliação
  • Wang X; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Pandey AK; St Jude Proteomics Facility, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
  • Mulligan MK; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Williams EG; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Mozhui K; Laboratory of Integrative and Systems Physiology, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
  • Li Z; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Jovaisaite V; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Quarles LD; Laboratory of Integrative and Systems Physiology, School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
  • Xiao Z; Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Huang J; Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Capra JA; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Chen Z; Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Taylor WL; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
  • Bastarache L; Department of Human Genetics, University of California, Los Angeles, California 90095, USA.
  • Niu X; Molecular Resource Center, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Pollard KS; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
  • Ciobanu DC; Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.
  • Reznik AO; Gladstone Institutes, San Francisco, California 94158, USA.
  • Tishkov AV; Division of Biostatistics and Institute for Human Genetics, University of California, San Francisco, California 94158, USA.
  • Zhulin IB; Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
  • Peng J; Animal Science Department, University of Nebraska, Lincoln, Nebraska 68583, USA.
  • Nelson SF; Joint Institute for Computational Sciences, University of Tennessee-Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.
  • Denny JC; Joint Institute for Computational Sciences, University of Tennessee-Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.
  • Auwerx J; Joint Institute for Computational Sciences, University of Tennessee-Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA.
  • Lu L; St Jude Proteomics Facility, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.
  • Williams RW; Department of Human Genetics, University of California, Los Angeles, California 90095, USA.
Nat Commun ; 7: 10464, 2016 Feb 02.
Article em En | MEDLINE | ID: mdl-26833085
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Regulação da Expressão Gênica / Predisposição Genética para Doença Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Variação Genética / Regulação da Expressão Gênica / Predisposição Genética para Doença Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Ano de publicação: 2016 Tipo de documento: Article