Using Procalcitonin in Septic Shock to Guide Antibacterial Therapy.
Dimens Crit Care Nurs
; 35(2): 66-73, 2016.
Article
em En
| MEDLINE
| ID: mdl-26836597
ABSTRACT
Over the last decade, the biomarkers procalcitonin and C-reactive protein have gained interest in sepsis research. Procalcitonin is a unique biomarker that is specific to bacterial infection and has demonstrated utility in the risk stratification of patients with potential life-threatening bacterial infections. In addition, procalcitonin has been documented as having a role in reducing the rate of unnecessary antibiotics while positively impacting antibiotic resistance rates and cost savings. The purposes of this review article are to discuss the clinical relevance of C-reactive protein and procalcitonin as diagnostic and prognostic markers for sepsis with a focus on the use of serial procalcitonin levels as a component of antibiotic stewardship programs. The federal government has recently become invested in combating the progression of antibiotic resistance; a 5-year national plan has been developed to address these concerns. Establishing a reliable antibiotic stewardship program is one of the goals of this national plan.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Choque Séptico
/
Proteína C-Reativa
/
Calcitonina
Limite:
Humans
Idioma:
En
Revista:
Dimens Crit Care Nurs
Ano de publicação:
2016
Tipo de documento:
Article