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Isolation of Middle East Respiratory Syndrome Coronavirus from a Patient of the 2015 Korean Outbreak.
Park, Wan Beom; Kwon, Nak-Jung; Choe, Pyoeng Gyun; Choi, Su-Jin; Oh, Hong Sang; Lee, Sang Min; Chong, Hyonyong; Kim, Jong-Il; Song, Kyoung-Ho; Bang, Ji Hwan; Kim, Eu Suk; Kim, Hong-Bin; Park, Sang Won; Kim, Nam Joong; Oh, Myoung-Don.
Afiliação
  • Park WB; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Laboratory of Infection & Immunity, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
  • Kwon NJ; Macrogen, Seoul, Korea.
  • Choe PG; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Choi SJ; Laboratory of Infection & Immunity, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
  • Oh HS; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Lee SM; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Chong H; Macrogen, Seoul, Korea.
  • Kim JI; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, Korea.
  • Song KH; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Bang JH; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Kim ES; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Kim HB; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Park SW; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
  • Kim NJ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Laboratory of Infection & Immunity, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
  • Oh MD; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Laboratory of Infection & Immunity, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.
J Korean Med Sci ; 31(2): 315-20, 2016 Feb.
Article em En | MEDLINE | ID: mdl-26839489
During the 2015 outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) in Korea, 186 persons were infected, resulting in 38 fatalities. We isolated MERS-CoV from the oropharyngeal sample obtained from a patient of the outbreak. Cytopathic effects showing detachment and rounding of cells were observed in Vero cell cultures 3 days after inoculation of the sample. Spherical virus particles were observed by transmission electron microscopy. Full-length genome sequence of the virus isolate was obtained and phylogenetic analyses showed that it clustered with clade B of MERS-CoV.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Coronavirus / Coronavírus da Síndrome Respiratória do Oriente Médio Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Revista: J Korean Med Sci Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Coronavirus / Coronavírus da Síndrome Respiratória do Oriente Médio Limite: Animals / Humans País/Região como assunto: Asia Idioma: En Revista: J Korean Med Sci Ano de publicação: 2016 Tipo de documento: Article