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Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists.
Emert-Sedlak, Lori A; Loughran, H Marie; Shi, Haibin; Kulp, John L; Shu, Sherry T; Zhao, Jielu; Day, Billy W; Wrobel, Jay E; Reitz, Allen B; Smithgall, Thomas E.
Afiliação
  • Emert-Sedlak LA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of School of Medicine, Pittsburgh, PA 15219 USA.
  • Loughran HM; Fox Chase Chemical Diversity Center, Inc., Doylestown, PA 18902 USA.
  • Shi H; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of School of Medicine, Pittsburgh, PA 15219 USA.
  • Kulp JL; Conifer Point Pharmaceuticals, Doylestown, PA 18902 USA.
  • Shu ST; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of School of Medicine, Pittsburgh, PA 15219 USA.
  • Zhao J; Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261 USA.
  • Day BW; University of Pittsburgh Drug Discovery Institute, Pittsburgh, PA 15260 USA.
  • Wrobel JE; Department of Pharmaceutical Sciences, University of Pittsburgh School of Pharmacy, Pittsburgh, PA 15261 USA.
  • Reitz AB; University of Pittsburgh Drug Discovery Institute, Pittsburgh, PA 15260 USA.
  • Smithgall TE; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260 USA.
Bioorg Med Chem Lett ; 26(5): 1480-1484, 2016 Mar 01.
Article em En | MEDLINE | ID: mdl-26852364
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Anti-HIV / Produtos do Gene nef do Vírus da Imunodeficiência Humana / Bibliotecas de Moléculas Pequenas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Anti-HIV / Produtos do Gene nef do Vírus da Imunodeficiência Humana / Bibliotecas de Moléculas Pequenas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2016 Tipo de documento: Article