Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress.

Lin, Chen; Zhao, Xinyuan; Sun, Desen; Zhang, Lingda; Fang, Wenpan; Zhu, Tingjia; Wang, Qiang; Liu, Botao; Wei, Saisai; Chen, Guangdi; Xu, Zhengping; Gao, Xiangwei

Lin, Chen; Zhao, Xinyuan; Sun, Desen; Zhang, Lingda; Fang, Wenpan; Zhu, Tingjia; Wang, Qiang; Liu, Botao; Wei, Saisai; Chen, Guangdi; Xu, Zhengping; Gao, Xiangwei.

Afiliação

Lin C; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Zhao X; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Sun D; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Zhang L; Program in Molecular Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
Fang W; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Zhu T; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Wang Q; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Liu B; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Wei S; University of Massachusetts Medical School, Program in Molecular Medicine, Worcester, MA, 01605, USA.
Chen G; Program in Molecular Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.
Xu Z; Institute of Environmental Medicine, Zhejiang University School of Medicine, Hangzhou, China.
Gao X; Program in Molecular Cell Biology, Zhejiang University School of Medicine, Hangzhou, China.

Sci Rep ; 6: 21133, 2016 Feb 16.

Article em En | MEDLINE | ID: mdl-26878911

Assuntos

Células Epiteliais Alveolares/metabolismo; Folistatina/genética; Fator 2 Relacionado a NF-E2/metabolismo; Nanopartículas; Estresse Oxidativo; Dióxido de Silício; Ativação Transcricional; Animais; Apoptose/genética; Linhagem Celular; Expressão Gênica; Humanos; Masculino; Proteínas de Membrana/genética; Camundongos; NADPH Oxidase 1; NADPH Oxidase 5; NADPH Oxidases/genética; Nanopartículas/efeitos adversos; Espécies Reativas de Oxigênio/metabolismo; Dióxido de Silício/efeitos adversos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação Transcricional / Dióxido de Silício / Estresse Oxidativo / Folistatina / Fator 2 Relacionado a NF-E2 / Nanopartículas / Células Epiteliais Alveolares Limite: Animals / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article

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