Topical carbonic anhydrase inhibitors in macular edema associated with Alström syndrome.
Ophthalmic Genet
; 37(4): 427-429, 2016 12.
Article
em En
| MEDLINE
| ID: mdl-26894450
ABSTRACT
BACKGROUND:
Alström syndrome is a rare genetic ciliopathy caused by a mutation in the ALMS1 gene. The syndrome is characterized by cone-rod dystrophy, dilated myocardiopathy, childhood obesity and sensorineural hearing loss. To date, cystoid macular edema has not been reported.METHODS:
A female affected by Alström syndrome developed bilateral cystoid macular edema evidenced by optical coherence tomography. A topical carbonic anhydrase inhibitor was prescribed.RESULTS:
Complete resolution of the cystoid macular edema was achieved, though visual acuity did not improve.CONCLUSIONS:
Topical carbonic anhydrase inhibitors may have a role in the treatment of macular edema in syndromic retinal dystrophies such as Alström syndrome.Palavras-chave
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sulfonamidas
/
Tiofenos
/
Inibidores da Anidrase Carbônica
/
Edema Macular
/
Síndrome de Alstrom
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Infant
Idioma:
En
Revista:
Ophthalmic Genet
Ano de publicação:
2016
Tipo de documento:
Article