Cellular and subcellular context determine outputs from signaling biosensors.

Devost, Dominic; Audet, Nicolas; Zhou, Cynthia; Kobayashi, Hiroyuki; Bonin, Hélène; Lukashova, Viktorya; Le Gouill, Christian; Bouvier, Michel; Hébert, Terence E

Devost, Dominic; Audet, Nicolas; Zhou, Cynthia; Kobayashi, Hiroyuki; Bonin, Hélène; Lukashova, Viktorya; Le Gouill, Christian; Bouvier, Michel; Hébert, Terence E.

Afiliação

Devost D; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, Canada.
Audet N; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, Canada.
Zhou C; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, Canada.
Kobayashi H; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada.
Bonin H; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada.
Lukashova V; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada.
Le Gouill C; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada.
Bouvier M; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC, Canada.
Hébert TE; Department of Pharmacology and Therapeutics, McGill University, Montréal, QC, Canada.

Methods Cell Biol ; 132: 319-37, 2016.

Article em En | MEDLINE | ID: mdl-26928550

Assuntos

Técnicas Biossensoriais; Transdução de Sinais; Núcleo Celular/enzimologia; Ativação Enzimática; Fator de Crescimento Epidérmico/farmacologia; MAP Quinases Reguladas por Sinal Extracelular/metabolismo; Transferência Ressonante de Energia de Fluorescência; Células HEK293; Células HeLa; Humanos; Sistema de Sinalização das MAP Quinases; Receptores Acoplados a Proteínas G/metabolismo; Acetato de Tetradecanoilforbol/farmacologia

Palavras-chave

Biosensors; G protein-coupled receptors; GPCRs; Resonance energy transfer; Signal profiling; Signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Transdução de Sinais Limite: Humans Idioma: En Revista: Methods Cell Biol Ano de publicação: 2016 Tipo de documento: Article

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