3,4-Dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, attenuates acetaminophen (APAP)-induced liver injury through activation of Nrf-2.

Xue, Huiting; Xie, Wenyan; Jiang, Zhihui; Wang, Meng; Wang, Jian; Zhao, Hongqiong; Zhang, Xiaoying

Xue, Huiting; Xie, Wenyan; Jiang, Zhihui; Wang, Meng; Wang, Jian; Zhao, Hongqiong; Zhang, Xiaoying.

Afiliação

Xue H; a College of Veterinary Medicine, Xinjiang Agricultural University , Urumqi , PR China and.
Xie W; b College of Veterinary Medicine, Northwest A&F University , Yangling , PR China.
Jiang Z; b College of Veterinary Medicine, Northwest A&F University , Yangling , PR China.
Wang M; b College of Veterinary Medicine, Northwest A&F University , Yangling , PR China.
Wang J; b College of Veterinary Medicine, Northwest A&F University , Yangling , PR China.
Zhao H; b College of Veterinary Medicine, Northwest A&F University , Yangling , PR China.
Zhang X; a College of Veterinary Medicine, Xinjiang Agricultural University , Urumqi , PR China and.

Xenobiotica ; 46(10): 931-9, 2016 Oct.

Article em En | MEDLINE | ID: mdl-26931552

Assuntos

Ácido 3,4-Di-Hidroxifenilacético/farmacologia; Substâncias Protetoras/farmacologia; Quercetina/metabolismo; Acetaminofen; Animais; Doença Hepática Induzida por Substâncias e Drogas; Camundongos; Microbiota; Fator 2 Relacionado a NF-E2/metabolismo; Estresse Oxidativo/efeitos dos fármacos

Palavras-chave

3,4-Dihydroxyphenylacetic acid; Nrf-2; acetaminophen; hepatic detoxification; quercetin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quercetina / Ácido 3,4-Di-Hidroxifenilacético / Substâncias Protetoras Limite: Animals Idioma: En Revista: Xenobiotica Ano de publicação: 2016 Tipo de documento: Article

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