[Pharmacovigilance update]. / Pharmacovigilance.
Rev Med Suisse
; 12(500): 75-9, 2016 Jan 13.
Article
em Fr
| MEDLINE
| ID: mdl-26946710
ABSTRACT
The main pharmacovigilance updates in 2015are reviewed. Sofosbuvir amiodarone interaction risk of severe bradycardia. Dasabuvir clopidogrel interaction increased dasabuvir concentrations and potential risk of QTprolongation. SGLT2 inhibitors risks of diabetic acidocetosis and bone fracture. Dabigatran therapeutic drug monitoring may improve benefit-risk ratio. Ibuprofen at higher dosage, vascular risks are comparable to coxibs. Pregabaline, gabapentine potential for abuse and addiction. Varenicline potentiates alcohol's effects. Codeine contra-indicated as cough medicine under the age of twelve. Valproate strengthened warnings on the risks of valproate use in pregnancy. Dimethylfumarate rare observations of progressive multifocal leucoencephalopathy. Ustekinumab rare observations of erythrodermia.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Farmacovigilância
Limite:
Humans
Idioma:
Fr
Revista:
Rev Med Suisse
Ano de publicação:
2016
Tipo de documento:
Article