Detection of Epidermal Growth Factor Receptor Mutations in Lung Adenocarcinoma: Comparing Cobas 4800 EGFR Assay With Sanger Bidirectional Sequencing.

Ardakani, Nima Mesbah; Giardina, Tindaro; Grieu-Iacopetta, Fabienne; Tesfai, Yordanos; Carrello, Amerigo; Taylor, Jeremy; Robinson, Cleo; Spagnolo, Dominic; Amanuel, Benhur

Ardakani, Nima Mesbah; Giardina, Tindaro; Grieu-Iacopetta, Fabienne; Tesfai, Yordanos; Carrello, Amerigo; Taylor, Jeremy; Robinson, Cleo; Spagnolo, Dominic; Amanuel, Benhur.

Afiliação

Ardakani NM; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia. Electronic address: nima.mesbahardakani@health.wa.gov.au.
Giardina T; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia.
Grieu-Iacopetta F; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia.
Tesfai Y; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia.
Carrello A; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia.
Taylor J; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia.
Robinson C; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia.
Spagnolo D; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia; University of Western Australia, School of Pathology and Laboratory Medicine, Perth, Western Australia, Australia.
Amanuel B; Department of Anatomical Pathology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia, Australia; University of Western Australia, School of Pathology and Laboratory Medicine, Perth, Western Australia, Australia.

Clin Lung Cancer ; 17(5): e113-e119, 2016 09.

Article em En | MEDLINE | ID: mdl-26961433

Assuntos

Adenocarcinoma/genética; Receptores ErbB/genética; Neoplasias Pulmonares/genética; Reação em Cadeia da Polimerase em Tempo Real/métodos; Análise de Sequência de DNA/métodos; Adenocarcinoma de Pulmão; Adulto; Idoso; Idoso de 80 Anos ou mais; Reações Falso-Negativas; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Mutação; Reprodutibilidade dos Testes; Sensibilidade e Especificidade; Fatores de Tempo

Palavras-chave

Cobas assay; EGFR mutations; Lung adenocarcinoma; Sanger sequencing; Tyrosine kinase inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenocarcinoma / Análise de Sequência de DNA / Reação em Cadeia da Polimerase em Tempo Real / Receptores ErbB / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Lung Cancer Ano de publicação: 2016 Tipo de documento: Article

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