HBx-upregulated lncRNA UCA1 promotes cell growth and tumorigenesis by recruiting EZH2 and repressing p27Kip1/CDK2 signaling.

Hu, Jiao-Jiao; Song, Wei; Zhang, Shao-Dan; Shen, Xiao-Hui; Qiu, Xue-Mei; Wu, Hua-Zhang; Gong, Pi-Hai; Lu, Sen; Zhao, Zhu-Jiang; He, Ming-Liang; Fan, Hong

Hu, Jiao-Jiao; Song, Wei; Zhang, Shao-Dan; Shen, Xiao-Hui; Qiu, Xue-Mei; Wu, Hua-Zhang; Gong, Pi-Hai; Lu, Sen; Zhao, Zhu-Jiang; He, Ming-Liang; Fan, Hong.

Afiliação

Hu JJ; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
Song W; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
Zhang SD; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
Shen XH; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
Qiu XM; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
Wu HZ; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
Gong PH; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
Lu S; The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.
Zhao ZJ; Department of Medical Genetics and Developmental Biology, Medical School of Southeast University, The Key Laboratory of Developmental Genes and Human Diseases, Ministry of Education, Southeast University, Nanjing, China.
He ML; CUHK Shenzhen Research Institute, Shenzhen, China.
Fan H; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong.

Sci Rep ; 6: 23521, 2016 Mar 24.

Article em En | MEDLINE | ID: mdl-27009634

Assuntos

Carcinogênese/genética; Transformação Celular Viral/genética; Proteína Potenciadora do Homólogo 2 de Zeste/genética; Neoplasias Hepáticas/genética; RNA Longo não Codificante/genética; Transativadores/genética; Animais; Proliferação de Células; Quinase 2 Dependente de Ciclina/genética; Inibidor de Quinase Dependente de Ciclina p27/genética; Regulação Neoplásica da Expressão Gênica; Humanos; Neoplasias Hepáticas/virologia; Proteínas de Membrana; Camundongos; Camundongos Nus; Transplante de Neoplasias; Serina Endopeptidases; Transdução de Sinais; Transfecção; Proteínas Virais Reguladoras e Acessórias

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transativadores / Transformação Celular Viral / RNA Longo não Codificante / Carcinogênese / Proteína Potenciadora do Homólogo 2 de Zeste / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2016 Tipo de documento: Article

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