Evaluation of TOPKAT, Toxtree, and Derek Nexus in Silico Models for Ocular Irritation and Development of a Knowledge-Based Framework To Improve the Prediction of Severe Irritation.

Bhhatarai, Barun; Wilson, Daniel M; Parks, Amanda K; Carney, Edward W; Spencer, Pamela J

Bhhatarai, Barun; Wilson, Daniel M; Parks, Amanda K; Carney, Edward W; Spencer, Pamela J.

Afiliação

Bhhatarai B; Toxicology & Environmental Research and Consulting, Dow Chemical Company , 2020 Dow Center, Midland, Michigan 48674, United States.
Wilson DM; Toxicology & Environmental Research and Consulting, Dow Chemical Company , 2020 Dow Center, Midland, Michigan 48674, United States.
Parks AK; Toxicology & Environmental Research and Consulting, Dow Chemical Company , 2020 Dow Center, Midland, Michigan 48674, United States.
Carney EW; Toxicology & Environmental Research and Consulting, Dow Chemical Company , 2020 Dow Center, Midland, Michigan 48674, United States.
Spencer PJ; Toxicology & Environmental Research and Consulting, Dow Chemical Company , 2020 Dow Center, Midland, Michigan 48674, United States.

Chem Res Toxicol ; 29(5): 810-22, 2016 05 16.

Article em En | MEDLINE | ID: mdl-27018716

Assuntos

Olho/efeitos dos fármacos; Irritantes/toxicidade; Modelos Teóricos; Animais; Simulação por Computador; Humanos; Relação Quantitativa Estrutura-Atividade

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Olho / Irritantes / Modelos Teóricos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Chem Res Toxicol Ano de publicação: 2016 Tipo de documento: Article

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