Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends.

Ti, Shih-Chieh; Pamula, Melissa C; Howes, Stuart C; Duellberg, Christian; Cade, Nicholas I; Kleiner, Ralph E; Forth, Scott; Surrey, Thomas; Nogales, Eva; Kapoor, Tarun M

Ti, Shih-Chieh; Pamula, Melissa C; Howes, Stuart C; Duellberg, Christian; Cade, Nicholas I; Kleiner, Ralph E; Forth, Scott; Surrey, Thomas; Nogales, Eva; Kapoor, Tarun M.

Afiliação

Ti SC; Laboratory of Chemistry and Cell Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
Pamula MC; Laboratory of Chemistry and Cell Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
Howes SC; Biophysics Graduate Group, University of California, Berkeley, CA 94720, USA.
Duellberg C; The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK.
Cade NI; The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK.
Kleiner RE; Laboratory of Chemistry and Cell Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
Forth S; Laboratory of Chemistry and Cell Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA.
Surrey T; The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK.
Nogales E; Life Sciences Division, Lawrence Berkeley National Lab, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California Berkeley, Berkeley, CA 94720, USA.
Kapoor TM; Laboratory of Chemistry and Cell Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA. Electronic address: kapoor@mail.rockefeller.edu.

Dev Cell ; 37(1): 72-84, 2016 Apr 04.

Article em En | MEDLINE | ID: mdl-27046833

Assuntos

Cinesinas/metabolismo; Microtúbulos/metabolismo; Tubulina (Proteína)/genética; Tubulina (Proteína)/metabolismo; Sítios de Ligação/genética; Linhagem Celular; Humanos; Espectrometria de Massas; Mutação Puntual/genética; Polimerização; Ligação Proteica/genética; Conformação Proteica; Estrutura Terciária de Proteína

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tubulina (Proteína) / Cinesinas / Microtúbulos Limite: Humans Idioma: En Revista: Dev Cell Ano de publicação: 2016 Tipo de documento: Article

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